| Metric | Q3'25 | Q4'25 | Change |
|---|---|---|---|
| Revenue | $11.12B (+5% YoY) | $12.21B (+7% YoY) | +200 bps acceleration |
| Adjusted EPS | $5.79 (+10% YoY) | $6.57 (+8% YoY) | -200 bps deceleration |
| Adjusted Operating Margin | 23.3% (+100 bps YoY) | 23.6% (-30 bps YoY) | -130 bps sequential deterioration |
| Organic Growth | 3% | 3% | Flat despite easier comps |
| Life Sciences Solutions Revenue | ~$2.6B (8% growth) | ~$3.1B (13% growth) | +500 bps acceleration |
| Analytical Instruments Revenue | ~$1.8B (5% growth) | ~$1.8B (1% growth) | -400 bps deceleration |
| Pharma/Biotech End Market | mid-single digit | high single-digit | Accelerated but vague |
| Academic/Government | low single digit decline | low single digit decline | No improvement despite budget clarity |
| Free Cash Flow (Full Year) | $3.3B YTD through Q3 | $6.34B guidance implies $3.0B in Q4 | Massive Q4 FCF assumption required |
| 2026 Organic Growth Guidance | 3-6% framework for '26-'27 | 3-4% for 2026 | Lowered to bottom of range |
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